Home : Unsafe Drugs : Singulair

Singulair Side Effects

Name: Singulair
Generic: Montelukast
Manufacturer: Merck
Date approved: February 20, 1998
Status: Prescription only, approved status being reviewed by the FDA
Approved uses: Preventative treatment of asthma and seasonal allergies
Off-Label uses: None
Side effects:
  • Stomach pain
  • stomach or intestinal upset
  • heartburn
  • tiredness
  • fever
  • stuffy nose
  • cough
  • flu
  • upper respiratory infection
  • dizziness
  • headache
  • rash
  • possible connection to increased suicidal thoughts
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Singulair (Montelukast)

Singulair is an asthma medication that acts by being a leukotriene inhibitor. Leukotrienes are chemicals the body releases when one breathes in an allergen (such as pollen). These chemicals cause swelling in the lungs and tightening of the muscles around airways, which can result in asthma symptoms. Singulair is proscribed to prevent asthma attacks in adults and children as young as 12 months old. It is also used to relieve runny nose and sneezing caused by allergies in adults and children as young as 6 months old.

In March 2008, reports emerged linking Singulair to increased suicidal thoughts among patients taking the medication. On March 27th, 2008, the FDA announced it was reviewing a possible connection between Singulair and suicidal behavior in adults and children, after receiving reports of mood and behavior changes, suicidal thinking and suicide in patients who had taken the drug. The FDA has recommended that until further information is available, health care professionals and caregivers should monitor patients taking Singulair for any suicidal behaviors or thoughts. Upon the completion of the investigation, the FDA will give its recommendation as to whether Singulair should continue being proscribed to asthma and allergy sufferers.

Singulair FDA Warnings - Possible Connection to Suicidal Thoughts

Singulair, generically known as montelukast sodium, is a medication manufactured and distributed through the pharmeceutical conglomerate Merck and Co. In the last year alone, Merck has changed the language on the prescribing information four times to include information on a range of newly reported side effects: tremors, anxiousness, depression and suicidal behavior. None of these symptoms were initially listed on the medication, nor did they surface in the controlled studies Merck performed in an analysis of more than 11,000 patients in 40 clinical trials. read more

Living With Asthma

There are currently almost 20 million Americans suffering from asthma, and approximately 45 percent of these individuals are children, according to the National Heart Lung and Blood Institute (NHLBI). Asthma is often associated with allergies, but not all individuals suffering from asthma also suffer from allergies. Signs and Symptoms of Asthma. read more

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Singulair FDA Information

FDA Statement on Foodborne E. coli O157:H7 Outbreak in Spinach--Update: Wednesday, October 4, 2006

View the Singulair FDA Information page here

Singulair News Articles

Asthma and Allergy Patients Prescribed Montelukast Instead of First Line Therapy and Shows Low Rate of Persistence

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Singulair Newsfeeds

What's Medicines Not To Take When Taking Ranitidine 150 Mg?

Earnings Preview: Merck report comes after drug OK

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Singulair Wikipedia

Montelukast

Asthma

View the Singulair Wikipedia page here

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