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Singulair

Singulair is an asthma medication that acts by being a leukotriene inhibitor. Leukotrienes are chemicals the body releases when one breathes in an allergen (such as pollen). These chemicals cause swelling in the lungs and tightening of the muscles around airways, which can result in asthma symptoms. Singulair is proscribed to prevent asthma attacks in adults and children as young as 12 months old. It is also used to relieve runny nose and sneezing caused by allergies in adults and children as young as 6 months old.

In March 2008, reports emerged linking Singulair to increased suicidal thoughts among patients taking the medication. On March 27th, 2008, the FDA announced it was reviewing a possible connection between Singulair and suicidal behavior in adults and children, after receiving reports of mood and behavior changes, suicidal thinking and suicide in patients who had taken the drug. The FDA has recommended that until further information is available, health care professionals and caregivers should monitor patients taking Singulair for any suicidal behaviors or thoughts. Upon the completion of the investigation, the FDA will give its recommendation as to whether Singulair should continue being proscribed to asthma and allergy sufferers.

Fast Facts

Name: Singulair
Generic: Montelukast
Manufacturer: Merck
Date approved: February 20, 1998
Status: Prescription only, approved status being reviewed by the FDA
Approved uses: Preventative treatment of asthma and seasonal allergies
Off-Label uses: None
Side effects: Stomach pain, stomach or intestinal upset, heartburn, tiredness, fever, stuffy nose, cough, flu, upper respiratory infection, dizziness, headache, rash, possible connection to increased suicidal thoughts
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Singulair FDA Warnings - Possible Connection to Suicidal Thoughts

Singulair, generically known as montelukast sodium, is a medication manufactured and distributed through the pharmeceutical conglomerate Merck and Co. It is used primarily for the prevention and... read more

Living With Asthma

There are currently almost 20 million Americans suffering from asthma, and approximately 45 percent of these individuals are children, according to the National Heart Lung and Blood Institute... read more

View the Singulair Main Articles page here

FDA Information Related to Singulair

December 2006 Monthly Safety Labeling

FDA Statement on Foodborne E. coli O157:H7 Outbreak in Spinach--Update: Wednesday, October 4, 2006

View the Singulair FDA Information page here

MSN Newsfeeds Related to Singulair

Mild Persistent Asthma — Polling Results

Ignorance isn’t bliss, but it is reason to sell

View the Singulair MSN Newsfeeds page here

News Articles Related to Singulair

US agency rejects Schering drug - International Herald Tribune

Depakote, epilepsy -- chicagotribune.com

View the Singulair News Articles page here

Wikipedia Entries Related to Singulair

Montelukast

Leukotriene antagonist

View the Singulair Wikipedia Entries page here

Books Related to Singulair

Montelukast, fluticasone propionate similarly cut ED visits for asthma.(Clinical Rounds)(emergency department ): An article from: Family Practice News

Rofecoxib, Montelukast Combo Cut Migraines.(Brief Article): An article from: Family Practice News

View the Singulair Books page here

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